Rehmania Plant

IRIDOID GLYCOSIDES

MONOTERPEN

MOLITOSIDES

REHMANIOSIDE- A,B,C,D

MULTIMINERAL- Ca, Cu, Zinc

AMIO ACIDS

GLUCOSAMINE

B-SETOSTEROL

OLIGOSACCHARIDE

Effect of administration of the standardized extract of Ginkgo biloba leaves on learning, memory and exploratory behavior was estimated in water maze and hole-board tests. Rats (18-month old) received for three months at doses: 50, 100 and 150 mg/kg b.w. per day. After completion of the behavioral experiment, concentrations of neurotransmitters were estimated in selected brain regions. ANOVA demonstrated significant differences in the content of monoamines and metabolites between the treatment groups compared to the control. The increased level of 5-hydroxytryptamine (5-HT) in the hippocampus and 5-HIAA (5-HT metabolite) in the prefrontal cortex correlated positively with the retention of spatial memory. Positive correlation between platform crossings in SE during the probe trial and neurotransmitter turnover suggest improvement of spatial memory. Long-term administration of Ginkgo biloba extract can improve spatial memory and motivation with significant changes in the content and metabolism of monoamines in several brain regions.

Reference : Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland.

Functions

a) IRIDOID GLUCOSIDES, MONOTERPEN, MALITOSIDES-

Iridoid Glycosides, Monoterpen, Glucosamine, Molitosides combined act as streptozotocin (STZ) which reduction in plasma glucose level by enhanced in c-reactive protein (CRP) concentration. It can also activate Beta cell and Alfa cell of Pancreas to control secreation Insulin and Glucagon.

b) OLIGOSACCHARIDE-

Oligosaccharide (ROS) decrease blood suger level by glucose metabolism.

c) GLUCOSAMINE-

Glucosamine can reduce Diabetic Neuropathy. Glucosamine also can regenerate of broken bone muscles and tissues.

d) REHMANIOSIDE- A, B, C, D-

Rehmanioside- A,B,C,D effective remady for fever and colds, inflamation and dizziness.

e) Multimineral- Ca, Cu, Zn-

Multimineral- Ca, Cu, Zn acts as immunosupressive. Also effective on autoimmune disease sush as Rheumatoid Athrities, Fibromyalgia, Multiple sclerosis.

REFERENCE-

1) Journal of Ethnopharmacology, volume 90, Issue 01, January 2004, Page 39-43.
2) The American Journal of Chinese Medicin, Volume 36, Issue 06, 2008.
3) Foster, Steven and Yue chongxi: Herbal Emissaries: Bringing Chinese Herbs to the West. Healing Arts Press 1992.
4) Bone, K. and N. Burgess: How To Prescribe Herbal Medicine. 2nd Ed. Warwick. MediHerb Ltd. 1992.
5) Bone, K.: Post Graduate Course in Phytotherapy. Warwick. MediHerb Ltd. 1990
6) Usher, G.: A Dictionary of Plants Used by Man. London, England. Constable and Company Ltd. 1974.
7) Yeung, Him Che: Handbook of Chinese Herbal Formulas. 2nd Ed. Redwing Book Co. 1985.